Class Discussion Summaries

A summary of biophysical chemistry course discussions at Institute of biochemistry and biophysics, university of Tehran.

Cooperativity and hydrophobicity

Cooperativity is a defining feature of protein folding, but its thermodynamic and structural origins are not completely understood. By constructing consensus ankyrin repeat protein arrays that have nearly identical sequences, we quantify cooperativity by resolving stability into intrinsic and interfacial components.

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